Capsule Supplier Produces Acid Resistant Capsule

BioVXR Acid Resistant HPMC Capsules
An excellent choice for delivery acid-sensitive ingredients

Acid vulnerable ingredients like probiotic products on the market contains strains that cannot survive the passage through the stomach acid and without protection only few of the bacteria will reach your intestines which is where they can colonize. BioVXR acid resistant HPMC capsules are designed to safely deliver the formulation into the intestinal tracts for dietary supplement industry.

BioVXR acid resistant HPMC capsules offer unique properties of acid resistance in low pH environmnt but dissoloves in a netural pH environment, which protects acid-vulnerable ingredients from stomach acid and release in intestinal tract. BioVXR capsules are well-suited for probiotic, enzyme, collagen and acid-sensitive ingredients. With advantages of HPMC capsules, low moisture capsules make it well-suited for moisture sensitive & hygroscopic formulations.

No additional chemical solvents processing or other coated protection required. Instead of coated processing, using BioVXR capsules with characteristics of acid resistance can help supplement makers reduce destruction of ingredients during additional production, manufacturing cost and the complexity of adding acid-resistant properties. It is helpful to shorten new product development process and verification and your new product can be launched to market in shorter period of time.

• Dissolution Test

*Reference: USP 40 – Acetaminophen Capsule, <711> Dissolution
*Indicator for observation：After 120 minutes of the pH1.2 environment, the dissolution rate must be lower than 10%. After 45 minutes of the pH6.8 environment, the dissolution rate must be higher than 80%.

 BioVXR acid resistant HPMC capsules
After 120 minutes of the pH1.2 environment, the dissolution rate of BioVXR is lower than 10%, which has protection for ingredient. After 45 minutes of the pH6.8 environment, the dissolution rate of BioVXR reached 89.18%, which most of the absorption occurred in intestinal tract.

Other delayed release capsules
After 120 minutes of the pH1.2 environment, the dissolution rate of delayed release capsules are higher than 10%, which have weak protection for ingredient. After 45 minutes of the pH6.8 environment, the dissolution rate of delay released capsules reached 32.19%, which less than half of the ingredient has been released.

• Benefit of BioVXR

✓  Outstanding resistance to gastric acid
✓  Suited for probiotics, enzymes and other acid sensitive products
✓  Available sizes： 00, 0, 1
✓  ETO Free, Non-GMO, Allergen Free, Preservative Free, BSE/TSE Free
✓  Low moisture HPMC capsules
✓  US & EU & Taiwan Patents
✓  US FDA DMF No. 030931
✓  Vegetarian society & Halal & Kosher certified

 *If you need customized capsules with titanium dioxide free colors, please contact us：sales@dfc.com.tw